在SARS-CoV-2感染和新发性心房动之间存在关联
Bar Rosh1, Ibrahim Naoum2, Ofra Barnett-Griness3
1Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
International journal of cardiology
|August 31, 2023
概括
感染SARS-CoV-2显著增加了新发性心房动 (NOAF) 的风险. 这项研究证实了COVID-19和发展NOAF之间的强烈关联,突出了关键的公共卫生问题.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 心房动 (AF) 导致显著的发病率和死亡率.
- 新出现的证据表明SARS-CoV-2感染与新发性AF (NOAF) 之间存在联系,但需要进一步调查.
- 需要对SARS-CoV-2和NOAF之间的关联进行严格的检查.
研究的目的:
- 调查SARS-CoV-2感染与新发性心房动 (NOAF) 的发生之间的关联.
- 为了量化SARS-CoV-2感染后NOAF的风险.
主要方法:
- 一项嵌套病例控制研究在2,931,046名成年人的队列中进行.
- 18,981名NOAF患者与189,810名对照进行了匹配.
- 使用条件后勤回归和滞后时间分析来评估关联,控制潜在偏差.
主要成果:
- 感染SARS-CoV-2与NOAF风险增加显著相关 (调整的OR,4.24).
- 在延迟时间分析后,这种关联仍然显著,在20天内逐渐减弱.
- 负对照暴露 (腰部疼痛) 与NOAF的相关性很小.
结论:
- SARS-CoV-2 感染与新发性心房的风险大大增加有关.
- 这些发现强调了监测COVID-19感染后心脏并发症的重要性.
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