在ICU肺部的流行病学和临床模式:一个法国多中心的回顾性研究
Vinca Montméat1, Vincent Bonny1, Tomas Urbina1
1Intensive Care Unit, Saint-Antoine University Hospital, APHP, Sorbonne University, Paris, France.
Chest
|August 31, 2023
概括
患有肺的重症患者经常患有多微生物感染,其中Enterobacteriaceae,金黄色葡萄球菌和Pseudomonas aeruginosa是常见的. 菌感染和替代疗法独立地预测了ICU中的死亡率.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 肺部的危急病患者的流行病学和管理不太清楚.
- 肺部瘤是重症监护室 (ICU) 中的一个严重疾病.
研究的目的:
- 研究患有肺的重症患者的临床和微生物特征.
- 为了确定管理策略和风险因素,在ICU死亡率在这个患者群体.
主要方法:
- 使用国际疾病分类,第10次修订代码 (2015-2022,法国) 的回顾性,观察性,多中心研究.
- 使用多变量逻辑回归来确定与ICU死亡率相关的因素.
主要成果:
- 总共分析了171名患有肺的ICU患者. 常见的病原体包括肠杆菌 (31%),金黄色葡萄球菌 (22%) 和空气菌 (19.3%). 多微生物感染发生在35.6%的患者中.
- 在ICU中的死亡率为21.5%. 死亡率的独立预测因素是年龄较大,置换疗法和真菌感染. 排水或手术没有显著影响死亡率.
- 临床表现包括疲劳,发烧和呼吸障碍;在21.7%的患者中报告了血栓塞.
结论:
- 在ICU中的肺是严重的,通常是多微生物感染,在三分之一以上的病例中需要进行干预.
- 真菌感染和需要替代疗法是死亡率的重要预测因素.
- 需要进一步的前性研究来优化抗菌药物治疗和源控制策略,以获得更好的患者结果.
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