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在中度至重度喘的成年人中,饮食炎症指数和临床结果测量
Edith Visser1, Kim de Jong2, Tim van Zutphen3
1Department of Epidemiology, Medical Centre Leeuwarden, Leeuwarden, the Netherlands; Department of Sustainable Health, Faculty Campus Fryslân, University of Groningen, Leeuwarden, the Netherlands.
The journal of allergy and clinical immunology. In practice
|August 31, 2023
概括
预炎性饮食似乎并没有使中度至重度喘的成年人喘的结果恶化. 需要进一步的研究来确认饮食变化是否可以改善喘患者的肺部健康.
科学领域:
- 营养科学 营养科学
- 肺部病理学 肺部病理学
- 免疫学 免疫学 免疫学
背景情况:
- 饮食通过营养驱动的免疫调节显著影响肺部健康.
- 饮食炎症指数 (DII) 量化了饮食模式的炎症潜力.
研究的目的:
- 调查DII,特定食物组和成人喘结局之间的关联.
- 评估喘患者的饮食与临床,功能和炎症标志物之间的关系.
主要方法:
- 对109名中度至重度喘成年人的横截面研究 (2019年6月至2021年10月).
- 通过3天的食物日记来评估饮食摄入量,以计算DII和食物组消费.
- 结果包括肺功能测试,6分钟的步行距离,喘控制问卷,生活质量,医疗利用,呼出的氧化和血液炎症标志物 (白细胞,乙氨基,IL-6).
- 用多变量回归分析来确定关联.
主要成果:
- 在62%的参与者中,主发炎性饮食 (DII > 0) 普遍存在,但与喘严重程度无关.
- 促炎症饮食始终与降低强迫生命能力 (预测%) 相关.
- 在DII或食品组与临床喘结果或大多数炎症标志物之间没有发现显著的关联. 抗炎饮食显示出非显著的趋势,即排出的氧化含量较高.
结论:
- 这项研究没有支持一种预炎性饮食会使中度至重度喘成年人的喘结果恶化的假设.
- 限制包括研究设计和饮食评估方法.
- 建议进行进一步的实验研究,以探索饮食干预措施对喘管理的影响.
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