在急性中风中使用简单的NCCT测量与MRI相比,对皮层和皮下脑缩的评估
Tanaporn Jaroenngarmsamer1,2, Faysal Benali1,3, Joachim Fladt4,5
1From the Department of Clinical Neurosciences (T.J., F. Benali, J.F., N.S., F. Bala, M.D.H., M.G., A.G.), University of Calgary, Calgary, Alberta, Canada tanaporn.jn@gmail.com.
AJNR. American journal of neuroradiology
|August 31, 2023
概括
非对比CT (NCCT) 可以评估中风后的大脑缩,皮质下缩测量显示与MRI有很强的相关性. 在NCCT上皮质缩被低估了,但与MRI有很好的一致性.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 脑缩是大脑储备的关键指标,也是大脑承受损伤的能力,例如中风.
- 与MRI成像相比,非对比CT (NCCT) 测量大脑缩的可靠性尚未得到充分证实.
研究的目的:
- 为了将NCCT上的实用脑缩测量与急性缺血性中风患者的MR成像进行比较.
- 评估NCCT和MR成像之间的皮质和皮质下缩评估的一致性和相关性.
主要方法:
- 从ESCAPE-NA1试验中对NCCT和24小时MRI成像数据进行后期分析.
- 使用全球皮质缩量表测量皮质缩;使用间尾距离与内表宽度 (CC/IT) 关系测量皮质下缩.
- 使用Gwet的协议系数计算协议 1;使用Pearson相关系数计算相关性.
主要成果:
- 与MRI成像相比,NCCT低估了皮质缩严重程度 (23.8%与44.3%相比).
- 在NCCT上进行的皮质缩评估表明与MRI成像 (Gwet的系数>0.784) 有实质性的一致性.
- 皮下缩测量 (CC/IT比) 显示了NCCT和MR成像之间强烈的相关性 (皮尔森相关性=0.746).
结论:
- 对新兴NCCT的简单测量可以评估大脑缩.
- NCCT是评估皮下缩的一个可行的工具,与MRI成像有很强的相关性.
- 虽然NCCT皮质缩测量与MRI成像相关性很好,但它们往往低估了严重程度.
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