在诊断和管理的最新情况非腹小肠多重症
Laura Lucaciu1, Tomonori Yano2, Jean Christophe Saurin3
1Royal Free Unit for Endoscopy, The Royal Free Hospital and UCL Institute for Liver and Digestive Health, London, UK.
Best practice & research. Clinical gastroenterology
|August 31, 2023
概括
对于Peutz-Jeghers综合征的胃肠道监测应从8岁开始. 超过15毫米的小肠多需要治疗以防止内分泌,新的内镜技术正在出现.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 遗传性胃肠多重症综合征 遗传性胃肠多重症综合征
背景情况:
- 内镜技术的进步已经改变了非腹膜小肠多重症的诊断和治疗.
- 遗传性多重症综合征,包括皮茨-杰格斯综合征 (PJS),家族腺瘤多重症 (FAP) 和青少年多重症综合征 (JPS),在小肠监测和管理方面存在独特的挑战.
研究的目的:
- 为非型小肠多症提供诊断和管理策略的最新概述,重点关注遗传多症综合征.
- 根据综合征类型和息肉大小,突出目前对内镜监测间隔和息肉切除值的建议.
主要方法:
- 关于PJS,FAP和JPS中小肠多的内镜监测和管理的当前文献和指导方针的审查.
- 讨论新兴的内镜技术,如缺血性多斑切除术和内镜减少内.
主要成果:
- 对于PJS,囊内镜监测应从8岁开始,如果多大于15毫米,需要治疗以预防内.
- 对于FAP,建议在25岁左右对近端结核进行初始查,并进行个性化十二指肠监测间隔;建议切除1厘米以上的腺瘤.
- 在JPS中小肠的参与是罕见的,主要是十二指肠,没有指示进行远端小肠检查.
结论:
- 定制的内镜监测和及时干预对于在遗传综合征中管理小肠多重症至关重要.
- 新兴的内镜技术为聚管理和并发症预防提供了有前途的替代方案.
- 遵守综合征特异性指导方针和考虑多体特征对于最佳的患者结果至关重要.
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