基底动脉封闭的位置和临床结果:来自ATTENTION多中心注册表的数据
Shuai Yu1,2, Xiaocui Wang1, Zhiliang Guo1
1Department of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Journal of neurointerventional surgery
|August 31, 2023
概括
对于用内血管治疗治疗的急性基底动脉封闭,近端和中间封闭与远端封闭相比,与更糟糕的结果和更高的死亡率有关. 这一发现对于预测患者预后至关重要.
科学领域:
- 神经学 神经学
- 血管外科 血管外科
- 干预性放射学 干预性放射学
背景情况:
- 急性基底动脉封闭是一种严重的疾病,具有显著的发病率和死亡率.
- 内血管治疗是急性基底动脉封闭的主要干预措施.
研究的目的:
- 为了研究封闭血管位置对接受急性基底动脉封闭症内血管治疗的患者预后结果的影响.
- 为了比较基底动脉内远端,中端和近端阻塞部位的结果.
主要方法:
- 分析来自ATTENTION注册表的患者数据.
- 在不同封闭位置的基线特征的比较.
- 应用单变量和多变量回归分析来确定闭塞位置对结果的影响.
主要成果:
- 分析了1672名患者:583名远端,540名中部,549名近端闭塞.
- 与远端闭塞相比,近端和中间闭塞与不良结果 (mRS 0-3) 和死亡率增加有显著的关联.
- 在封闭血管位置和症状性内出血之间没有发现任何关联.
结论:
- 靠近和中间基底动脉封闭与临床结果不佳和内血管治疗后死亡率增加有关.
- 阻塞位置是急性基底动脉阻塞管理中的一个重要的预后因素.
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