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中年血液静止测量,20年认知衰退,以及发生痴呆症

Aozhou Wu1, A Richey Sharrett1, Aaron R Folsom1

  • 1From the Johns Hopkins University (A.W., A.R.S., A.L.G., J.C.), Bloomberg School of Public Health, Baltimore, MD; University of Minnesota (A.R.F.), School of Public Health, Minneapolis; Department of Epidemiology (A.A.), Rollins School of Public Health, Emory University, Atlanta, GA; Laboratory of Behavioral Neuroscience (K.A.W.), Intramural Research Program, National Institute on Aging, Baltimore; National Institute of Neurological Disorders and Stroke Intramural Program (R.F.G.), NIH, Bethesda, MD; Sanofi (A.M.R.), Cambridge, MA; and Division of Neurocritical Care (A.L.C.S.), Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia.

Neurology
|August 31, 2023
PubMed
概括

中年血液静止测量,包括激活的部分血栓形成时间 (aPTT) 和XVIII因子,与长期认知能力下降和痴呆风险有关. 这些发现表明,血管病理可能导致血液凝固因素与大脑健康之间的关联.

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