在手术后72小时内输血后儿童死亡率的种族差异
Brittany L Willer1, Christian Mpody1, Oluwadara Nafiu2
1Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Journal of pediatric surgery
|August 31, 2023
概括
与白人儿童相比,接受手术后输血的少数民族儿童面临更高的死亡风险. 这项研究突出了手术结果的种族差异,强调需要进一步调查促成因素.
科学领域:
- 儿科手术 儿科手术
- 医疗保健服务研究 医疗服务研究
- 健康差异 在健康上的差异
背景情况:
- 手术后出血和输血与死亡风险增加有关.
- 少数民族儿童面临更高的手术并发症风险.
- 这项研究调查了在输血后儿童手术死亡率与种族的关联.
研究的目的:
- 检查种族与儿科手术死亡率之间的关系.
- 为了比较黑人,西班牙裔和"其他"种族儿童的死亡率与术后输血后白人儿童的死亡率.
主要方法:
- 使用NSQIP-PPUF (2012-2021) 的回顾性队列研究.
- 包括在住院手术后72小时内接受输血的儿童 (<18岁).
- 后勤回归分析了30天所有原因死亡率的风险调整几率比率 (aOR).
主要成果:
- 输血后的整体死亡率为2.5% (46,200名输血患者).
- 与白人儿童相比,黑人儿童的死亡率是白人儿童的1.24倍 (aOR:1.24;95%CI,1.03-1.51).
- 与白人儿童相比,西班牙裔儿童的死亡率是白人儿童的1.19倍 (aOR: 1.19; 95%CI, 1.02-1.39).
结论:
- 需要术后输血的少数民族儿童的死亡率比白人儿童高.
- 需要进一步的研究来探索导致差异的管理方面的不良事件和种族差异.
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