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Updated: Jul 17, 2025

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle
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高衰老限制了体细胞重编程期间的细胞可塑性.

Bogdan B Grigorash1,2, Dominic van Essen1, Guixian Liang3,4

  • 1Institute for Research on Cancer and Aging of Nice (IRCAN), Université Côte d'Azur, INSERM, CNRS, Nice, France.

Nature cell biology
|August 31, 2023
PubMed
概括

移除衰老细胞可以增强体细胞的四因素重编程 (4FR),使其变成类似于全能干细胞的干细胞. 这一过程通过促进细胞可塑性和逆转衰老标志物,使老化的组织恢复青春.

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