牙发育规则使微观进化与现存和灭绝的灵长类动物的宏观进化保持一致
Fabio A Machado1, Carrie S Mongle2,3, Graham Slater4
1Department of Integrative Biology, Oklahoma State University, Stillwater, OK, USA. fabio.machado@okstate.edu.
Nature ecology & evolution
|August 31, 2023
概括
将发育生物学 (evo-devo) 与定量遗传学相结合,弥合了微观和宏观进化的尺度. 生物知情模型揭示了灵长类动物牙进化的走廊式适应性景观.
科学领域:
- 进化生物学是进化的生物学.
- 发育生物学 (evo-devo) 是一个学科.
- 定量遗传学 是一个量子遗传学.
背景情况:
- 经典的宏观进化研究往往将宏观和微观进化过程分开.
- 定量遗传学模型难以预测形态学的长期进化模式.
- 发育研究 (evo-devo) 提供了潜在的联系,但缺乏表型多样化的正式框架.
研究的目的:
- 确定使用evo-devo模型量化生物变异是否可以增强比较模型.
- 弥合微观进化和宏观进化尺度之间的差距.
- 将evo-devo融入现代合成中,以了解宏观进化原因.
主要方法:
- 制定一个正式的框架,以应用evo-devo模型来表型多样化.
- 使用生物信息的形态空间与定量遗传学一起.
- 在现存和已灭绝的种群中分析一套关于灵长类动物下进化的综合数据集.
主要成果:
- 生物信息的形态空间与定量遗传学相结合,使微观和宏观进化尺度之间的无过渡成为可能.
- 生物学上不知情的形态空间无法提供这种整合能力.
- 灵长类动物牙进化的适应性景观类似于走廊,走廊内的形态变化几乎是中性的.
结论:
- 提出的框架成功地将evo-devo整合到进化生物学中.
- 这种方法为评估宏观进化的最终原因提供了一个操作方法.
- 了解发育变异是连接微观和宏观进化过程的关键.
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