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Updated: Jun 17, 2026

Profiling of Methyltransferases and Other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry CCMS
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库林-RING E3网络的基于活动的分析,采用特定的形状探测器

Lukas T Henneberg1, Jaspal Singh2, David M Duda3,4

  • 1Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.

Nature chemical biology
|August 31, 2023
PubMed
概括

研究人员开发了一种新型合成抗体,用于检测激活的库林-RING泛素酶 (CRL) 复合体. 该工具揭示了CRL网络如何在不同细胞和刺激时发生变化,从而影响蛋白质降解.

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Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment

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Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale

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相关概念视频

Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...