微生物生长的差异取决于半固体肠道营养补充剂的类型
Sachiko Omotani1, Kanaha Murakami1, Arisa Naka1
1Faculty of Pharmacy, Osaka Ohtani University, 3-11-1, Nishikiori-Kita, Tondabayashi, Osaka, 584-8540, Japan.
Journal of pharmaceutical health care and sciences
|August 31, 2023
概括
肠道营养中的微生物生长因产品类型而异. pH显著影响细菌生长,而Candida albicans在所有测试的配方中都生长,这凸显了对准备挂 (RTH) 制剂的严格感染控制的需要.
科学领域:
- 微生物学 微生物学
- 临床营养学 临床营养学
- 感染控制 感染控制
背景情况:
- 肠道营养补充剂被广泛使用,但由于其富含营养的性质,需要谨慎管理.
- 日本缺乏准备挂 (RTH) 肠道营养制剂的确立的感染控制方法,这增加了护理人员的依赖.
- 这项研究调查了各种肠道营养物质在污染后的微生物生长差异.
研究的目的:
- 评估不同肠道营养成分配方对微生物生长的影响.
- 确定影响肠道营养产品中微生物增殖的因素.
- 为了告知RTH肠道营养的感染控制策略.
主要方法:
- 九种肠道营养产品进行了测试.
- 在产品中注射了大肠杆菌,Serratia marcescens和Candida albicans的培养物.
- 细菌计数是在25°C的0,4,8和24小时测量.
主要成果:
- 大肠杆菌和Serratia marcescens在特定的半固体和液体肠道营养产品中生长.
- 其他肠道营养产品显示细菌数量下降.
- 不管配方如何,Candida albicans在所有九种测试的肠道营养产品中都显示出生长.
结论:
- pH 是影响肠道营养产品细菌生长差异的主要因素.
- 菌的生长独立于pH值,在所有测试的配方中都出现.
- 半固体肠道营养物质的污染可能导致微生物生长,需要采取强有力的感染控制措施.
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