估计乳腺癌查计划对死亡率,病例死亡率和DALYs的差异,跨越金+国家
Sumaira Mubarik1,2, Saima Shakil Malik3, Zhang Yanran1,4
1Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, 185 Donghu Road, Wuhan, 430071, Hubei, China.
BMC medicine
|August 31, 2023
概括
乳腺癌查 (BCS) 在金+国家显著降低死亡率. 更先进的查方法,如乳房造影,除了解决风险因素之外,对于降低乳腺癌负担和改善结果至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 许多研究证实乳腺癌查 (BCS) 可以降低死亡率.
- 在金+国家中,BCS对病例死亡率和残疾的影响仍未得到充分研究.
- 这项研究调查了金+国家在各种方法中的BCS有效性.
研究的目的:
- 检查各种乳腺癌查 (BCS) 方法与年龄标准化死亡率,病例死亡率和残疾调整寿命年 (DALYs) 在金+国家之间的关联.
- 评估生物和社会人口统计学风险因素对这些地区乳腺癌发病率的影响.
- 提供关于BCS有效性的国家和经济视角.
主要方法:
- 一项利用混合效应多层回归模型的生态研究.
- 来自2019年全球疾病负担研究的乳腺癌 (BC) 死亡率,发病率和DALYs的数据与国家/区域BCS可用性和类型相结合.
- 分析的BCS类型包括自我乳房检查 (SBE) /临床乳房检查 (CBE),乳房扫描 (MM) 和数字乳房扫描/超声波 (DMM/US).
主要成果:
- 更先进的BCS计划 (MM和/或SBE/CBE;DMM/US和/或之前的测试) 与单独使用SBE/CBE相比,与BC死亡率的降低有显著联系.
- 心血管疾病 (CVD) 存在,高BMI和吸烟 (积极吸烟和二手吸烟) 会增加BC死亡率和DALY率.
- 高收入和中等收入地区的BC死亡率,病例死亡率和DALY率低于低收入地区,在全国范围内实施BCS计划时.
结论:
- 乳房扫描和BCS的可用性与金+国家乳腺癌负担的减少有关,区域差异显著.
- 这些发现支持了乳房扫描查在国家一级的预防作用.
- 针对BCS相关的风险因素可以进一步减轻与乳腺癌相关的疾病负担.
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