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在COVID-19中预测急性肺栓塞
Ibrahim Koc1, Olgun Deniz2, Sevda Unalli Ozmen3
1Bursa City Hospital Pulmonary Medicine, Bursa, Turkey.
Medicine
|September 1, 2023
概括
在COVID-19患者中,较高的C反应蛋白 (CRP) 淋巴细胞比率 (CLR) 可以帮助诊断肺栓塞 (PE). 超过81的CLR建议对PE进行进一步调查,并表明死亡风险更高.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 临床病理学 临床病理学
背景情况:
- 急性肺栓塞 (PE) 是COVID-19患者的一个关键问题.
- 计算机断层扫描肺血管造影 (CTPA) 是PE诊断的黄金标准,但成本昂贵且无法普遍获得.
研究的目的:
- 评估具有成本效益的临床和实验室参数的实用性,包括C反应蛋白 (CRP) 淋巴细胞比率 (CLR) 和费里丁CRP比率 (FCR),用于诊断COVID-19患者的PE.
- 在这个患者群体中确定PE和死亡率的预测因素.
主要方法:
- 对127名被诊断患有PE的COVID-19患者和105名没有PE的患者进行了回顾性分析.
- 在初次入院时记录了临床数据,症状,呼吸速率,SpO2和实验室参数 (例如,CRP,费里丁,淋巴细胞,乙蛋白).
主要成果:
- 与没有PE的患者相比,患PE的患者表现出较低的乙氨基基基水平和较高的费里丁淋巴细胞比率和CLR.
- 在PE组中,呼吸短促和疲劳更为普遍.
- 升高的费里,CRP和CLR与增加的死亡风险有关.
- 降低埃索诺菲尔和增加CLR,D-二次体和CRP水平可能预测PE.
结论:
- 升高的CLR是COVID-19患者PE的强烈预测因素,与增加的死亡率有关.
- 超过81的CLR的COVID-19患者需要进一步对PE进行调查.
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