在接受内镜治疗的肝脑病变和急性水出血患者的全身麻醉:一项回顾性研究
Tao Chen1, Lin Wen2, Rui Zhong3
1Department of Digestive Endoscopy Center, Digestive Disease Center, Suining Central Hospital, Suining, China.
Medicine
|September 1, 2023
概括
带有气管输管的全身麻醉对于肝硬化的肝脏脑病变 (HE) 和急性水出血 (AVB) 患者是安全有效的. 这种方法改善了意识和临床结果而不增加死亡率,提供了可行的内镜治疗选择.
科学领域:
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 肝硬化患者的肝脏脑病变 (HE) 和急性水出血 (AVB) 的管理存在重大挑战和高死亡率.
- 在HE患者的内镜手术中,全身麻醉是复杂的,因为可能会产生神经复杂症.
研究的目的:
- 评估通用麻醉与气管管道输入在接受内镜手术的HE和AVB肝硬化患者的效果.
- 评估这种麻醉方法在改善HE和临床结果方面的安全性和有效性.
主要方法:
- 对36名HE和AVB肝硬化患者进行了回顾性研究.
- 在全身麻醉下进行内镜治疗的14名患者和接受非麻醉或药物治疗的22名控制患者之间的比较.
- 收集临床和实验室数据,包括死亡率,HE阶段和Child-Pugh分数.
主要成果:
- 总体死亡率为13.9%,麻醉 (14.3%) 和对照 (13.6%) 组的死亡率相似.
- 在两组中都改善了HE阶段;麻醉组的85.8%和对照组的72.7%恢复了意识 (P>0.05).
- 与手术前相比,麻醉组在出院时显示出Child-Pugh分数,类和HE阶段的显著改善.
结论:
- 带有气管输管的全身麻醉不会使AVB的肝硬化患者的脑病变严重程度恶化.
- 在全身麻醉和气管管道输入下进行内镜治疗是HE AVB患者的有效和安全选择,改善神经状态和临床参数.
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