在口腔潜在恶性疾病中评估平状体状况 - - 系统性审查
S Annapoorani1, N Gururaj1, V Abiraami Balambigai1
1Department of Oral and Maxillofacial Pathology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
Journal of pharmacy & bioallied sciences
|September 1, 2023
概括
在口腔潜在恶性疾病 (OPMDs) 中的DNA块化表明癌症风险. 基因化状态是预测恶性转变的可靠生物标志物,有助于早期检测和风险评估.
科学领域:
- 口腔病理学 口腔病理学
- 在瘤学瘤学.
- 生物标志物研究的研究.
背景情况:
- 表皮病变显示出像DNA内容变化这样的异常.
- 早期发现这些变化对于预防恶性瘤至关重要.
- 在口腔潜在恶性疾病 (OPMDs) 中的DNA块化可能标志着恶性转化潜力.
研究的目的:
- 系统地审查OPMDs中DNA ploidy状态的意义.
- 为了评估DNA ploidy作为恶性转变风险的生物标志物.
- 评估用于危险评估的性状态的可行性.
主要方法:
- 对OPMDs中DNA ploidy状态的研究进行系统审查.
- 评估各种方法来确定DNA ploidy.
- 作为恶性转变的预测指标,性状态的分析.
主要成果:
- 在OPMDs中,DNA ploidy 状态是显著的指标.
- 体状况可以作为预测恶性转变的独立生物标志物.
- 审查证实了评估OPMDs. ploidy的重要性.
结论:
- DNA ploidy 状态是预测OPMDs恶性转变的有价值生物标志物.
- 未来的研究应该探索吸烟者的口腔粘膜中的DNA ploidy 分析,以评估风险.
- 这种技术也可能有助于预测对恶性瘤的遗传倾向.
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