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Updated: Jul 17, 2025

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
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A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo

Published on: May 16, 2020

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与多克索鲁比相关的Acrocomia aculeata:心脏保护和抗癌活性

Tamaeh Monteiro-Alfredo1,2,3,4, Jéssica Maurino Dos Santos1, Kátia Ávila Antunes1

  • 1Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Frontiers in pharmacology
|September 1, 2023
PubMed
概括

阿克罗科米亚秋叶叶提取物 (EA-Aa) 增强了多克索鲁比辛的作用.

关键词:
巴西的塞拉多.抗氧化剂是一种抗氧化剂.波卡伊 波卡伊 波卡伊化疗的副作用 化疗的副作用澳门百家乐 澳门百家乐氧化应激是一种氧化应激.

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The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
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