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Updated: Jul 17, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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使用仿真VSV-NDV的瘤性病毒疗法协同支持RIG-I依赖检查点抑制剂免疫疗法

Janina Marek1, Lorenz Hanesch1, Teresa Krabbe1

  • 1Department of Internal Medicine II, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.

Molecular therapy oncolytics
|September 1, 2023
PubMed
概括

结合一个模拟性瘤性病毒 (VSV-NDV) 与抗细胞毒性T淋巴细胞相关蛋白4 (CTLA-4) 疗法显示出有前途. 这种组合会延缓瘤生长,并通过激活瘤细胞中的RIG-I信号来提高生存率.

关键词:
在RIG-I中,RIG-I是指RIG-I.这是一种抗CTLA-4的药物.免疫检查点抑制抑制免疫检查点抑制免疫疗法 免疫疗法恶性黑色素瘤是一种恶性黑色素瘤.科性病毒病毒.

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