成年美国人中便秘和严重抑郁症之间的关联:来自NHANES 2005-2010年的证据
Pengfei Wang1, Xia Shen2, Yan Wang3
1Department of Anorectal Surgery, China Academy of Chinese Medical Sciences Xiyuan Hospital, Beijing, China.
Frontiers in psychiatry
|September 1, 2023
概括
便秘与美国成年人的严重抑郁症有着显著的联系. 医疗保健提供者应在便秘患者中查抑郁症,以确保及时干预并防止症状恶化.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 便秘和严重抑郁症之间的关联需要进一步调查.
- 目前对这种并发症的研究有限,需要进行详细的检查.
研究的目的:
- 调查美国成年人中便秘和严重抑郁症之间的详细联系.
- 为了确定便秘是否是主要抑郁症的独立风险因素.
主要方法:
- 一项横截面研究利用了来自国家健康和营养检查调查 (2005-2010) 的12,352名成年人 (20岁以上) 的数据.
- 便秘定义为每周排便3次;使用患者健康问卷-9 (PHQ-9) 评估的大型抑郁症.
- 多变量逻辑回归模型用于计算调整的赔率比率 (ORs),并进行子组分析以确保结果的稳定性.
主要成果:
- 便秘的发病率为3.5% (430/12,352),主要抑郁症的发病率为8.3% (1030/12,352).
- 患有便秘的人患重度抑郁症的几率明显更高 (20.9%对比7.9%,p < 0.001).
- 经过调整后的分析证实了便秘和严重抑郁症 (OR: 2.20,95% CI: 1.68-2.87,p < 0.001) 之间存在显著的关联,这与众多混因素无关.
结论:
- 便秘与美国成年人的严重抑郁症有显著的关联.
- 临床医生应在出现便秘的患者中查抑郁症.
- 对便秘患者抑郁症的早期评估和干预对于防止病情恶化至关重要.
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