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Updated: Jul 31, 2026

Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins
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Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins

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在使用合成抗体的伴侣辅助RNA晶体学方面取得了进展

Hasan Al Banna1, Naba Krishna Das1, Manju Ojha1

  • 1Department of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, MD 21250, USA.

BBA advances
|September 1, 2023
PubMed
概括

确定RNA结构对于理解功能和开发治疗方法至关重要. 合成抗体碎片 (Fabs) 显示出作为结晶伴侣的承诺,通过X射线结晶学帮助RNA结构的确定.

关键词:
结晶的陪伴者 结晶的陪伴者复杂的Fab-RNA复合体使用Fab辅助的RNA晶体学在RNA结构中,RNA结构是RNA的结构.合成抗RNA的Fab合成在X射线晶体学.

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Monitoring Protein-RNA Interaction Dynamics In Vivo at High Temporal Resolution Using χCRAC09:15

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相关概念视频

Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...