在医疗保健中对病原性病毒和细菌进行侧向流量检测
Xuanxu Nan1, Xuesong Yao1, Li Yang2
1School of Materials Science and Engineering, Peking University; First Hospital Interdisciplinary Research Center, Peking University, Beijing 100871, P.R. China. ycui@pku.edu.cn.
The Analyst
|September 1, 2023
概括
侧流检测提供了与医疗保健相关的致病病毒和细菌的快速,经济高效的检测. 这篇评论强调了他们的方法和应用程序,以诊断护理点的诊断.
科学领域:
- 生物医学工程 生物医学工程
- 传染病诊断 传染病诊断 传染病诊断
- 照顾点检测检测 照顾点检测
背景情况:
- 由致病性病毒和细菌引起的与医疗相关的感染对全球健康构成重大风险.
- 传统的诊断方法往往缺乏及时干预所需的速度和可访问性.
- 侧流检测 (LFA) 由于其固有的优势,已成为一个有前途的替代方案.
研究的目的:
- 为检测致病病毒和细菌提供横向流量试验的全面审查.
- 探索LFA在病原体检测中的方法,器件组件,施工技术和各种应用.
- 确定开发新型LFA设备的机会,以对抗传染病并增强医疗保健.
主要方法:
- 对用于病原体检测的侧向流量测试技术现有文献的审查.
- 对LFA原理的分析,包括通过横向流和分析剂-生物受体结合的单向检测.
- 检查LFA的优点:快速检测,简单的制造,和成本效益的点的护理使用.
主要成果:
- 侧向流量测试显示,相对于传统的染色学方法来检测病原体,它具有显著的优势.
- 由于其速度,简单性和可负担性,LFA非常适合于护理点应用.
- 该审查涵盖了LFA发展的各个方面,从基本方法到实际应用.
结论:
- 侧向流量测试代表了对致病病毒和细菌的治疗点检测的理想格式.
- 在LFA技术的持续研究和开发具有促进传染病诊断的巨大潜力.
- 本综述为创建创新的LFA设备提供了有价值的见解,以改善全球医疗保健结果.
相关概念视频
01:23Flow Cytometry
The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...
In...
01:23Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
01:25Rapid Identification of Pathogens
MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...
01:24Automated Microbial Diagnostics
Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...