在新生儿的脚跟手术中使用糖镇痛
Janet Yamada1, Mariana Bueno2, Lucia Santos2
1Daphne Cockwell School of Nursing, Toronto Metropolitan University, Toronto, Canada.
The Cochrane database of systematic reviews
|September 1, 2023
概括
口服糖可能会降低经过脚刀手术的新生儿的疼痛评分. 然而,与其他非药物干预措施 (如母乳养或非营养吸) 相比,证据不确定.
科学领域:
- 新生儿疼痛管理 新生儿疼痛管理
- 基于证据的儿科医学
- 临床试验分析
背景情况:
- 新生儿在侵袭性手术中经常感到疼痛,比如跟.
- 口服糖是一种常用的干预措施,用于管理新生儿的手术疼痛.
- 评估糖与各种比较剂的疗效对于临床实践至关重要.
研究的目的:
- 为了评估口服糖对缓解新生儿在脚跟刺痛期间疼痛的有效性.
- 为了比较糖糖的疗效与安慰剂,非营养吸,葡萄糖,母乳养和其他方法.
- 评估与糖糖管理相关的即时和长期结果.
主要方法:
- 55项涉及6273名新生儿的随机对照试验的系统综述和元分析.
- 包括经过跟刀或其他轻微痛苦的手术的满期和早产新生儿.
- 使用标准Cochrane方法进行数据分析,报告平均差异和置信区间;用GRADE评估证据的确定性.
主要成果:
- 糖糖可能会降低早产婴儿疼痛概况 (PIPP) 的得分,与对照者相比,在30秒和60秒后的跟发射 (中度确定性证据).
- 与非营养吸 (NNS),母乳养,激光针和促进插入相比,证据对糖糖的作用非常不确定.
- 与葡萄糖相比,糖糖在疼痛评分上几乎没有差异,与母乳缩和皮肤对皮肤护理相比,糖糖在疼痛评分上几乎没有差异.
结论:
- 与没有干预相比,口服糖可能有效降低跟刺后的疼痛评分.
- 与其他非药物干预措施相比,糖糖的有效性是不确定的.
- 糖糖与其他非药理方法的联合使用需要谨慎,因为证据有限.
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