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Updated: Jul 17, 2025

Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs
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Published on: June 12, 2018

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脂类激酶PIP5K1A通过与核出口蛋白XPO5的相互作用来调节let-7微RNA生物发生

Chun Li1, Bohyung Yoon1, Giovanni Stefani1

  • 1Harvard Medical School Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

Nucleic acids research
|September 1, 2023
PubMed
概括

脂类激酶PIP5K1A通过与XPO5相互作用,调节microRNA (miRNA) 水平,影响let-7 miRNA生物发生. 这一发现揭示了PIP5K1A和miRNA通路之间的新联系,可能为癌症等疾病提供治疗途径.

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