偏头痛和心血管疾病死亡率之间的关联:基于人口的前性队列研究
Huanxian Liu1,2, Shuhua Zhang1,2,3, Zihua Gong1,2,4
1Department of Neurology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Headache
|September 1, 2023
概括
偏头痛与美国人口中心血管疾病 (CVD) 死亡率的增加有关. 这项研究发现了显著的关联,强调了将偏头痛视为心脏健康的危险因素的重要性.
科学领域:
- 心血管流行病学心血管流行病学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 关于不同人群中偏头痛和心血管疾病 (CVD) 死亡率之间的关联存在相互矛盾的结论.
- 对美国人口的全面评估对于澄清这种关系至关重要.
研究的目的:
- 评估美国偏头痛和心血管疾病 (CVD) 死亡率之间的关联.
- 为了确定可能改变这种关联的特定的人口和生活方式因素.
主要方法:
- 这是一项前性队列研究,利用了1999-2004年国家健康和营养检查调查 (NHANES) 的10,644名参与者的数据.
- 偏头痛状态由自我报告的严重头痛或偏头痛决定.
- 与2019年12月31日的国家死亡指数相关的死亡率数据;由ICD-10代码定义的CVD死亡率.
主要成果:
- 20.4%的参与者被诊断出偏头痛.
- 与没有偏头痛的人相比,患有偏头痛的人对心血管疾病死亡率 (1.30) 和全因死亡率 (1.23) 的调整风险比率 (HR) 显著更高.
- 亚组分析显示,女性,年轻成年人 (<45岁),非西班牙裔白人,BMI<30的个体,吸烟者,饮酒者和没有代谢综合征的人群中,心血管疾病死亡风险与偏头痛相关.
结论:
- 偏头痛独立地与美国人口中心血管疾病 (CVD) 死亡率的风险增加有关.
- 这些发现强调需要在心血管健康评估中将偏头痛视为潜在的风险因素.
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