芝加哥分类v4.0对酸负荷和异常阻抗-pH变量进行分层,比芝加哥分类v3.0和GERD更好
Mentore Ribolsi1, Lorenzo Marchetti1, Edoardo Savarino2
1Department of Digestive Diseases, Campus Bio Medico University of Rome, Roma, Italy.
The American journal of gastroenterology
|September 1, 2023
概括
芝加哥分类 (CC) v4.0对食道运动的标准对于诊断胃食道逆流病 (GERD) 比CC v3.0.0更为具体. 这次更新通过完善低运动性标准来改善GERD诊断.
科学领域:
- 胃肠病学 胃肠病学
- 食道生理学 食道生理学
- 诊断的标准 诊断的标准
背景情况:
- 胃食道逆流性疾病 (GERD) 的严重程度与食道体低运动性相关.
- 更新的芝加哥分类 (CC) 标准对GERD的诊断影响仍然不清楚.
研究的目的:
- 为了在患有GERD的患者中比较CC v3.0和CC v4.0之间的诊断.
- 评估CC v4.0对在GERD患者中鉴定食道运动障碍的影响.
主要方法:
- 使用了高分辨率计量和pH阻抗监测.
- 在247名GERD患者中,CC v3.0和CC v4.0的诊断结果进行了比较.
主要成果:
- 低运动性诊断显著下降,从45.3% (CC v3.0) 降至30.0% (CC v4.0).
- 在患有无效食道运动的患者中,病理性酸暴露从38% (CC v3.0) 增加到88% (CC v4.0).
- 基线阻抗和食道清除发现与CC v4.0的改善特异性一致.
结论:
- 与CC v3.0.0相比,CC v4.0低机动性标准对于支持GERD证据更为具体,而CC v3.0.0则更为具体.
- 更新的CC标准提高了GERD评估中食道功能的诊断准确性.
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