虚拟现实改善功能性消化不良的症状:随机,双盲,假冒控制的试点研究结果
David J Cangemi1, Marilia Montenegro1, Brennan M R Spiegel2
1Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA.
The American journal of gastroenterology
|September 1, 2023
概括
虚拟现实 (VR) 显著改善功能性消化不良的症状. 这种安全的治疗方法比假虚拟现实更能缓解症状,因此需要在更大规模的试验中进一步调查.
科学领域:
- 胃肠病学 胃肠病学
- 医疗技术 医疗技术 医学技术
- 精神病体医学是一种精神病体医学.
背景情况:
- 功能性消化不良 (FD) 是一种常见的胃肠道疾病,其特点是持续的上腹部症状.
- 目前FD的治疗选择对某些患者的疗效有限,需要新的治疗方法.
- 虚拟现实 (VR) 技术为治疗慢性疾病提供了潜在的非药物干预.
研究的目的:
- 评估虚拟现实 (VR) 作为功能性消化不良 (FD) 治疗的疗效.
- 评估VR干预在被诊断为FD的患者中的安全性.
- 为了比较主动VR与假VR在缓解FD症状方面的有效性.
主要方法:
- 一个随机对照试验设计被采用了2:1的分配比率为活跃与假虚拟现实.
- 诊断为功能性消化不良的患者被招募并随机分为两个组.
- 在两周的时间内,使用患者胃肠道疾病评估-症状严重程度指数 (PAGI-SYM) 量化测量症状严重程度.
主要成果:
- 活跃的VR组在整体PAGI-SYM得分上表现出明显更大的数值改善,与假VR组相比 (平均差异为-0.7与-0.4,P <0.001与P = 0.032).
- 积极的VR干预导致大多数PAGI-SYM子尺度的显著改善,腹部下部疼痛除外.
- 虽然一半的患者经历了不严重的不良反应,但仅有一名患者因不良事件而停止了研究,这表明了有利的安全性.
结论:
- 虚拟现实 (VR) 是一种安全有效的治疗方式,用于改善功能性消化不良 (FD) 患者的症状.
- 这些发现表明,VR为FD提供了一个有前途的非药物治疗选择,优于虚假干预.
- 建议进行更大规模的临床试验,以进一步验证这些结果,并探索FD的VR治疗的长期结果.
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