硬:一种新的工具,用于预测肝硬患者高风险的静脉动脉
Rui Gaspar1, Marco Silva1, Pedro Cardoso1
1Gastroenterology Department, Centro Hospitalar São João, Faculty of Medicine of the University of Porto, Porto, Portugal.
Journal of gastroenterology and hepatology
|September 1, 2023
概括
使用新的100赫兹探针进行腺弹性学,可以准确预测肝硬化患者的高风险静脉动脉. 这种非侵入性方法可以帮助避免不必要的上部内镜,以查门门高血压并发症.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 胃肠病学 胃肠病学
- 医疗成像医学成像
背景情况:
- 肝硬化是全球主要的健康问题,门高血压对其并发症有很大贡献.
- 测量肝静脉压梯度 (HVPG) 是侵入性的,昂贵的,并且仅限于专门的中心.
- 非侵入性标记物,如肝硬度和腺弹性图,对于评估门性高血压至关重要.
研究的目的:
- 为了评估硬度测量的准确性,使用新的100Hz探针.
- 预测肝硬化患者高风险食道静脉的存在.
- 为了确定脏硬的最佳切割值,以识别高风险的静脉动脉.
主要方法:
- 一项前性研究,涉及接受上部内镜检查的肝硬化患者.
- 盲目操作员使用100赫兹探针同时进行肝脏和脏弹性体检.
- 弹性体检结果与高风险静脉瘤的存在进行比较.
主要成果:
- 包括209名肝硬化患者;72.7%患有酒精性肝病.
- 脊髓弹性图的中位数为42.4kPa.
- 硬度的切线值为53.25kPa,对预测高风险变节的100%的灵敏度和72.6%的特异性.
- 这种切断可能可以节省76%的上部内镜,而Baveno指导方针为29.1%.
结论:
- 使用100赫兹探针进行肌弹性扫描是一种有效的非侵入性工具,用于预测肝硬化中高风险的静脉动脉.
- 硬度的53.25kPa截止值可以帮助避免不必要的上部内镜用于水查.
- 这种技术有望融入常规肝脏病学实践中.
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