在接受选择性全关节整形手术的患者中,金黄色葡萄球菌的殖民化和周围假肢关节感染:叙述性综述
Michael de Buys1, Krisantha Moodley2, Josip Nenad Cakic3
1Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa.
EFORT open reviews
|September 1, 2023
概括
在关节置换手术前对黄金葡萄球菌的查是有争议的. 全球脱殖可能会减少手术部位感染和成本,但建议采用考虑到当地因素的量身定制方法.
科学领域:
- 传染性疾病 传染性疾病
- 整形外科手术 整形外科手术
- 公共卫生 公共卫生
背景情况:
- 假肢周关节感染 (PJIs) 是全关节整形术 (TJA) 的一个重要并发症.
- 黄金葡萄球菌殖民是PJIs的主要可修改风险因素,增加了感染风险的十倍.
- 目前用于S. aureus脱殖的策略,包括查与通用方法相比,是有争议的.
研究的目的:
- 评估查和有针对性的脱殖民化与普遍脱殖民化的有效性和成本效益,以预防PJIs.
- 为优化TJA患者S. aureus去殖民化策略提供建议.
主要方法:
- 这项研究审查了有关S. aureus殖民和PJI的现有文献和流行病学数据.
- 与查/有针对性的非殖民化与普遍非殖民化相关的结果的比较分析.
- 在战略建议中考虑当地流行病学模式,资源可用性和后勤能力.
主要成果:
- 全面去殖民化策略与手术部位感染 (SSI) 的降低率有关.
- 全球脱殖民化可能会降低PJI的整体治疗成本.
- 建议根据特定的医疗保健环境为脱殖民化采取量身定制的方法.
结论:
- 在TJA患者中,S. aureus脱殖的最佳策略需要仔细考虑多种因素.
- 全面去殖民化为减少SSI和潜在的医疗保健成本提供了一个可行的选择.
- 实施基于当地环境的定制方法对于有效的PJI预防至关重要.
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