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Updated: Jul 17, 2025

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激活NEDD8的酶E1 UBA3通过NF-кB通路协调肺腺癌中免疫抑制的微环境

Xiongzhi Lin1,2, Shuhan Yang1,3, Caichuan Zhou1,3

  • 1Taizhou Central Hospital (Taizhou University Hospital), Taizhou University, Taizhou, Zhejiang, China.

Medical oncology (Northwood, London, England)
|September 1, 2023
PubMed
概括

通过增加免疫抑制细胞,UBA3蛋白和化途径促进肺癌免疫逃生. 阻断UBA3抑制了这种途径,减少了促进瘤的细胞因子和免疫细胞透.

关键词:
免疫抑制的微环境肺部腺癌瘤是肺部腺癌.这是一种NEDD8激活酶.核因子卡帕 B B 的核因子在UBA3中,UBA3是UBA3.

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