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Updated: Jul 17, 2025

Hemogenic Endothelium Differentiation from Human Pluripotent Stem Cells in A Feeder- and Xeno-free Defined Condition
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从人类多能干细胞生成造血细胞:方法,进展和挑战

Haiqiong Zheng1,2,3,4, Yijin Chen1,2,3,4, Qian Luo1,2,3,4

  • 1Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310012, China.

Cell regeneration (London, England)
|September 1, 2023
PubMed
概括

人类多能干细胞 (hPSCs) 可以产生许多血细胞类型. 为临床使用产生大规模,成熟,功能细胞仍然具有挑战性,但最近的方法提供了解决方案.

关键词:
血细胞是血液中的细胞.血液构成分化的分化.造血干细胞 造血干细胞 造血干细胞人类多能干细胞是人类多能干细胞.

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The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
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