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Updated: Jul 17, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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综合素β4诱导的上皮细胞转化为介质细胞的转变涉及miR-383介导的GATA6水平调节

Aswini Poyyakkara1, Grace R Raji1, K P Padmaja1,2

  • 1Department of Biochemistry and Molecular Biology, Central University of Kerala, Tejaswini Hills, Periye, Kasaragod, Kerala, 671316, India.

Molecular biology reports
|September 1, 2023
PubMed
概括

集成蛋白β4 (ITGB4) 信号传导通过AKT激活诱导上皮层-介质酶过渡 (EMT),导致miR-383准GATA6. 这一途径促进细胞迁移和入侵,突出了EMT相关疾病的新型治疗点.

关键词:
从上皮细胞转变为介质细胞的过渡.GATA6 GATA6 是一个数字.在ITGB4信号系统中.这里是 miR-3833.这是一种β-catenin.

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