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在息性癌症护理的预后研究中开发一个核心成果集:混合方法研究协议
Caitlin Spooner1, Bella Vivat1, Nicola White1
1Marie Curie Palliative Care Research Department, University College London, London, United Kingdom.
JMIR research protocols
|September 1, 2023
概括
这项研究旨在制定一个标准化的核心结果集,用于评估接受息治疗的晚期癌症患者的终身预后. 这将提高癌症预后的研究和临床实践的一致性.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 在瘤学瘤学.
- 临床试验 临床试验
背景情况:
- 关于晚期癌症患者生命末期预后的影响存在相互矛盾的发现,由于各种结果措施.
- 在息性癌症护理预后中标准化结果对于在不同研究中进行一致的评估和比较至关重要.
- 一个核心结果集确保了预测研究结果的统一选择和报告.
研究的目的:
- 开发一个核心成果集,用于衡量终身预后在息性癌症护理中的影响.
- 建立一种标准化的方法来评估晚期癌症患者的预后.
- 促进预后研究中的一致报告和试验间比较.
主要方法:
- 采用混合方法的方法,遵循有效性试验 (COMET) 倡议指南中的核心成果措施.
- 第一阶段:系统审查以确定用于预后研究的现有结果.
- 第二阶段:与患者,护理人员和临床医生的半结构面试;第三阶段:德尔菲调查和共识会议,以优先考虑和支持核心结果.
主要成果:
- 在2022年9月获得的伦理批准.
- 系统审查 (第一阶段) 完成并发表;从2023年7月开始招聘第二阶段.
- 研究预计将于2024年10月完成.
结论:
- 该协议概述了一种逐步的方法,用于开发一种核心成果集,用于息性癌症护理中的终身预后.
- 由此产生的核心结果集有可能通过使预后算法的一致评估和改善沟通来增强临床实践.
- 该倡议还将支持对关键利益相关者可接受的未来临床试验的设计.
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