在高出血风险患者的皮肤冠状动脉干预后,短暂的双重抗血小板治疗持续时间:系统综述和元分析
Kevin R Bainey1, Guillaume Marquis-Gravel2, Blair J MacDonald3
1Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta.
PloS one
|September 1, 2023
概括
在经过皮肤冠状动脉干预 (PCI) 的高出血风险患者中,短期双重抗血小板治疗 (DAPT) 1-3个月显著减少出血事件. 这种较短的持续时间是安全的,不会增加缺血风险,如MACE或支架血栓形成.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 穿皮冠状动脉干预 (PCI) 后的双重抗血小板疗法 (DAPT) 对于预防支架血栓形成和主要心血管不良事件 (MACE) 至关重要.
- 确定最佳的DAPT持续时间具有挑战性,特别是在高出血风险 (HBR) 患者中,长期治疗会增加出血并发症.
结论:
- 在接受PCI的高出血风险患者中,长达1-3个月的DAPT有效减少出血事件.
- 在不影响缺血保护的情况下,可以安全地在HBR患者中实施简短的DAPT.
- 建议在接受PCI的HBR患者考虑更短的DAPT持续时间.
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