苏丹的真菌感染:一个被低估的健康问题
Sarah A Ahmed1,2, Mawahib Ismail3, Mohamed Albirair4
1Center of Expertise in Mycology Radboudumc / Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
PLoS neglected tropical diseases
|September 1, 2023
概括
严重的真菌感染影响了苏丹的500万人,突出了严重的公共卫生负担. 对于这些常见疾病的诊断,治疗和监测,需要采取紧急行动.
科学领域:
- 医学真菌学 医学真菌学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,真菌病导致显著的发病率和死亡率,但它们的流行病学往往被低估.
- 估计严重真菌感染的负担对于有效的控制计划实施至关重要.
研究的目的:
- 通过风险人口模型估计苏丹严重真菌感染的负担.
- 为该地区管理真菌病的公共卫生战略提供信息.
主要方法:
- 利用基于面临真菌感染风险的人群的模型.
- 纳入当地,区域和国际数据用于流行和发病率计算.
- 包括易受感染的人群,如艾滋病毒,结核病,癌症,喘和COPD患者.
主要成果:
- 估计有500万苏丹人 (占人口的10%) 患有真菌性疾病.
- 估计的特定感染包括Tinea capitis (4.1M),复发性vulvovaginitis (631K),与艾滋病毒相关的真菌菌 (8K多例),以及各种Aspergillus感染 (86K多例).
- 湿疹瘤影响了16,837例 (36/100,000),而真菌鼻炎影响了93,600例.
结论:
- 在苏丹,严重的真菌感染非常普遍.
- 迫切需要加强诊断能力,促进治疗机会,并建立苏丹真菌病监测计划.
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