在肥胖男性的低或高强度饮食干预后,精子流动性的改善
Aditi Sharma1, Nikoleta Papanikolaou1, Sara Abou Sherif1
1Department of Metabolism, Digestion and Reproduction, Imperial College, London W12 0NN, UK.
The Journal of clinical endocrinology and metabolism
|September 1, 2023
概括
低能耗饮食 (LED) 和简短的饮食干预 (BDI) 改善了肥胖男性的精子运动. 需要进一步的研究来了解父亲的饮食干预对生育结果的影响.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 营养科学 营养科学
- 肥胖医学 肥胖医学
背景情况:
- 肥胖是男性不孕症的一个重要危险因素.
- 腹部外科手术没有证明精液质量有所改善.
- 新兴证据表明,低能耗饮食 (LED) 可能会提高精液质量.
研究的目的:
- 评估低能耗饮食 (LED) 与简短饮食干预 (BDI) 在改善肥胖男性的精液参数方面的有效性.
- 评估饮食干预措施对正常精子度和小精子精子的男性的精子运动的影响.
主要方法:
- 一项随机对照试验,涉及肥胖男性 (18-60岁) 具有正常精子度或小精子精子度.
- 参与者被随机分配到每天800卡路里LED16周或对照BDI16周.
- 精液参数,包括总运动率 (TM) 和渐进运动率 (PM),在基线和16周后进行了评估.
主要成果:
- 与基线相比,LED和BDI组都经历了显著的体重减轻.
- 在正常精子度的男性中,LED和BDI都导致TM和PM从基线显著增加.
- 在患有橄动物精子症的男性中,LED和BDI都使PM从基线显著改善,而TM在LED组中显示出改善.
- 在参与者分组中,LED和BDI组之间没有观察到干预后TM或PM的显著差异.
结论:
- 低能耗饮食 (LED) 和简短的饮食干预 (BDI) 似乎足以改善肥胖男性的精子运动性.
- 这项研究强调了饮食干预在管理与肥胖相关的男性不孕症方面的潜力.
- 需要进一步的研究来探索父亲的饮食干预对生育结果的长期影响.
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