复合生物工程蛋白质补充剂改善了 brojlers 的肠道健康和生长性能
Y T Tang1, S G Yin1, C F Peng1
1Key Laboratory for Animal Disease-Resistance Nutrition of Ministry of Education of China, Ministry of Agriculture and Rural Affairs of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, Sichuan, China.
Poultry science
|September 1, 2023
概括
复合生物工程蛋白 (CBP) 补充改善了 brojler 的生长,抗氧化能力和肠道健康. 最佳剂量为750mg/kg的CBP增强了肠道微生物群和免疫功能.
科学领域:
- 动物科学动物科学
- 生物技术是生物技术.
- 微生物学 微生物学
背景情况:
- 抗微生物 (AMP) 在畜牧业中被探索作为抗生素增长促进剂的替代品.
- 复合生物工程蛋白 (CBP),包括人工的Parasin I和plectasin蛋白质,需要对其在肉生产中的潜在益处进行调查.
研究的目的:
- 评估饮食中CBP补充剂对肉生长性能,肠道健康,抗氧化能力,免疫反应和肠道微生物群的影响.
主要方法:
- 总共有450只Arbor Acres雄性肉在6周内被食含有0.250,500,750或1,000毫克/公斤CBP的饮食.
- 分析了生长性能,血清抗氧化能力,肠道形态,基因表达 (紧密结节,粘素,细胞因子) 和菌群.
主要成果:
- 补充CBP显著增加了体重,平均每日增加和料摄入量.
- 观察到增强的抗氧化能力 (血清T-AOC,直肠GPx) 和改善的肠道形态 (十二指肠的高度/密室深度).
- 与肠道屏障功能 (克劳丁-1,奥克卢丁,MUC2) 和免疫反应 (IL-10,IL-6,IFN-γ,TNF-α) 相关的CBP调节的基因表达.
- 饮食中的CBP积极改变了肠道微生物群,增加了乳酸菌和减少了大肠杆菌的丰度.
结论:
- 食CBP补充剂通过增强抗氧化能力,肠道健康,免疫功能和肠道微生物群平衡,有效地提高肉生长性能.
- 750 mg/kg的CBP补充水平显示出最显著的有益影响.
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