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Updated: Jul 17, 2025

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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Published on: June 8, 2022

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与阿波利波蛋白M结合的基-1-酸盐通过激活S1P1和S1P4来抑制NETosis

Makoto Kurano1, Baasanjav Uranbileg1, Yutaka Yatomi1

  • 1Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|September 1, 2023
PubMed
概括

脂蛋白M (ApoM) 通过调节氨酸1-酸盐 (S1P) 信号传递来保护抗败血症诱导的NETosis. 针对ApoM/S1P轴可能为败血症和相关的凝血病提供新的治疗方法.

关键词:
阿波利波蛋白M是M的一种蛋白质.凝血病是一种凝血病.在 HDL 和 HDL 之间.基因组合物 基因组合物网症 (NETosis) 是一种疾病.作为一个中性粒细胞.器官受伤 器官受伤 器官受伤在 PKC PKC 里面,斯芬哥辛1-酸盐是一种酸盐.

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