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用计算方法分析和预测针对人类和类铁酶的抑制剂的结合模式

Federico Ricci1, Kristina Schira2, Lyna Khettabi3

  • 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. D'Alcontres 31, I-98166, Messina, Italy.

European journal of medicinal chemistry
|September 1, 2023
PubMed
概括

研究人员通过结合计算和实验方法开发了一种双向型铁酶抑制剂. 这种新化合物对类氨酸酶 (AbTYR) 和人类氨酸酶 (hTYR) 具有相似的疗效,为高颜色药物提供更快的查方法.

关键词:
4-(4-基) 是皮佩拉-1-基衍生物中的一种.计算方法 计算方法人类的铁酶酶.中的铁酶酶.

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