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基于与谷氨酸触媒相关的酶的系统分析确定了GPT2作为肺腺癌的新型免疫治疗点

Bolin Wang1, Jinli Pei2, Shengnan Xu2

  • 1Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, China; Department of Radiation Oncology and Shandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences Jinan, Shandong, China; Research Unit of Radiation Oncology, Chinese Academy of Medical Sciences, Jinan, Shandong, China.

Computers in biology and medicine
|September 1, 2023
PubMed
概括

向谷氨胺代谢,特别是GPT2,对肺腺癌 (LUAD) 治疗有希望. 抑制GPT2抑制瘤生长并增强抗瘤免疫力,为LUAD提供了一种新的治疗策略.

关键词:
GPT2 GPT2是什么意思谷氨酸酸酸盐转胺酶2 2谷氨胺的代谢过程免疫治疗是一种免疫疗法.肺部腺癌瘤是肺部腺癌.瘤微环境是一个微环境.

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