水中生长的雌激素化合物的潜在风险,水中生长的水中生长的水中生长
Marie Smutná1, Jakub Javůrek1, Luděk Sehnal1
1RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic.
Chemosphere
|September 1, 2023
概括
淡水植物浮游生物通常具有较低的雌激素性,对水生生物的风险最小. 即使是高密度的开花也不太可能导致与其他与开花相关的毒性相比,显著的雌激素效应.
科学领域:
- 环境科学 环境科学
- 生态毒理学 生态毒理学
- 水生生物学 水生生物学
背景情况:
- 关于淡水植物浮游生物的雌激素潜力及其对水生生态系统的影响,存在相互矛盾的报道.
- 之前的研究表明结果各不相同,有些人暗示副作用,有些人则表明没有雌激素活性或高估.
- 澄清这些不一致性对于准确的环境风险评估至关重要.
研究的目的:
- 为了研究淡水植物浮游生物生物质提取物的雌激素性.
- 为了比较环境繁殖和蓝藻和藻类实验室培养之间的雌激素性.
- 评估植物浮游生物提取物与模型雌激素17β-雌激醇 (E2) 的相互作用.
主要方法:
- 在体外报告者生物测试用于测试生物质提取物.
- 从实验室培养中测试了8种蓝藻和3种藻类.
- 分析了来自8个独立水体的环境水样本.
主要成果:
- 在开花和实验室样本中观察到不可检测或低雌激素性 (高达4.5 ng EEQ/g干质量).
- 与E2同时暴露显示了简单的添加相互作用;一些提取物在更高的E2度下表现出抗雌激素作用.
- 两种蓝藻菌种的雌激素性较低,在非常密集的开花中可能达到基于效应的触发值.
结论:
- 从淡水花和实验室培养中提取的浮游生物质提取物具有较低的雌激素潜力.
- 虽然在一些蓝藻细菌中检测到低雌激素性,但在现实的环境条件下,显著的雌激素风险不太可能发生.
- 与密集的淡水开花的其他有毒影响相比,雌激素效应可能很小.
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