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Updated: Jul 17, 2025

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抑制合成中的α-碳种族化,这种抑制是基于一种醇-性氨基保护群的

Yifei Zhou1, Hongjun Li1, Yi Huang1

  • 1State Key Laboratory of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, Department of Chemical Biology, College of Chemistry, Nankai University, Tianjin, 300071, China.

Nature communications
|September 1, 2023
PubMed
概括

一个新的醇可变的保护组,2,4-dinitro-6-phenyl-benzene sulfenyl (DNPBS),可以最大限度地减少固相合成 (SPPS) 中的副作用. 当与标准的Fmoc化学相结合时,DNPBS为复杂合成提供了一个正交的策略.

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