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通过in silico方法和in vitro微管聚合活性分子分析替代的乙烯胺作为潜在的微管向剂

Isadora Rocha De Abreu1,2, Allison Barkdull1,3, James R Munoz2

  • 1Clinical Systems Biology Group, Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA.

Scientific reports
|September 1, 2023
PubMed
概括

合成的乙胺可以通过改变微管的动态来影响大脑功能,类似于. 这项研究选了110种化合物,确定了影响微管聚合的特定分子,可能会影响神经可塑性.

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