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对于妊娠年龄和幼儿牙来说很小:BRISA队列研究
Juliana de Kássia Braga Fernandes1,2, Francenilde Silva de Sousa3,4, Cláudia Maria Coelho Alves1,5
1Programa de Pós-graduação em Saúde Coletiva, Universidade Federal do Maranhão, São Luís, MA, Brazil.
Scientific reports
|September 1, 2023
概括
对于妊娠年龄 (SGA) 来说出生小的儿童表现出对严重的幼儿虫 (S-ECC) 的敏感性增加. 这种关系是复杂的,受诊断标准和牙突发数量的影响,影响疾病风险暴露.
科学领域:
- 儿科牙科 儿科牙科
- 公共卫生 公共卫生
- 新生儿科学 新生儿科学
背景情况:
- 严重的幼儿 (S-ECC) 是一个重要的公共卫生问题.
- 对于妊娠年龄 (SGA) 来说出生小的儿童可能具有独特的健康脆弱性.
- 了解SGA和S-ECC之间的联系对于有针对性的预防策略至关重要.
研究的目的:
- 调查这样的假设:对于妊娠年龄 (SGA) 来说出生小的儿童更容易患上严重的幼儿 (S-ECC).
- 分析SGA对S-ECC发展的直接和间接影响.
- 探索诊断标准和牙喷发状态对这种关联的影响.
主要方法:
- 一项前性队列研究,涉及巴西东北部的865名12至30个月龄的儿童.
- S-ECC 定义为 腐烂的牙表面的比例.
- 根据克莱默标准和INTERGROWTH-21st标准定义的妊娠年龄小 (SGA).
- 用于估计直接和间接影响的结构方程建模.
主要成果:
- SGA证明了对S-ECC的直接和间接影响.
- 使用克莱默标准,在儿童中观察到SGA对S-ECC的积极直接影响≥12颗突发牙 (SFL=0.163,P=0.019).
- 使用INTERGROWTH-21st标准,在所有SGA儿童中发现SGA对S-ECC的负面直接影响 (SFL=-0.711,P<0.001).
- 年龄和牙突出的数量似乎改变了SGA儿童S-ECC的发生率.
结论:
- SGA和S-ECC之间的关系是复杂的,受SGA的定义和孩子的发育阶段 (牙数) 的影响.
- 喷发的牙的数量会影响暴露时间的卡里奥基因风险因素,介导SGA对S-ECC的影响.
- 需要进一步的研究来阐明这些复杂的相互作用,以便有效的早期干预计划.
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