使用Pirfenidone向转化生长因子β (TGF-β),这是结直肠癌中潜在的重定位治疗策略

Hamid Jamialahmadi1,2,3, Seyedeh Elnaz Nazari1, Hamid TanzadehPanah1,2,4

  • 1Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Scientific reports
|September 1, 2023
PubMed
概括

皮尔芬尼 (PFD),是一种转化生长因子β (TGF-β) 抑制剂,抑制了结直肠癌 (CRC) 细胞的增殖和迁移. 与5-甲 (5-FU) 结合的PFD显示了增强CRC治疗的潜力.

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