艾滋病毒阳性患者在ART治疗中的孤立原瘤:一个病例报告
Kevin K Wu1,2, Masoud Movassaghi3, Brittney DeClerck3
1Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. kevin.wu2@med.usc.edu.
BMC infectious diseases
|September 1, 2023
概括
在一个艾滋病毒阳性患者身上发现了一种罕见的原蛋白瘤,一种良性皮肤瘤. 这一案例凸显了在艾滋病毒患者皮下结节的差异诊断中考虑原蛋白瘤的重要性.
科学领域:
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
背景情况:
- 原瘤是一种罕见的良性结合组织瘤.
- 之前没有确立原瘤与人类免疫缺陷病毒 (HIV) 之间的相关性.
- 艾滋病毒患者可能表现出脂质缩或脂质瘤.
研究的目的:
- 在艾滋病毒阳性个体中报告一种孤立的原瘤的独特病例.
- 讨论这种罕见疾病的临床表现和组织病理学发现.
主要方法:
- 一个HIV阳性患者接受抗逆转录病毒疗法 (ART) 呈现皮下结节的案例研究.
- 病变的外科切除. 病变的外科切除.
- 切除的结节的组织病理学检查.
主要成果:
- 在头头皮上切除了一个7x4厘米的皮下结节.
- 组织病理学证实了厚厚的,随机排列的原体束,表明有原瘤.
- 原瘤被隔离,没有表皮变化.
结论:
- 这个案例详细介绍了一个艾滋病毒患者的孤立原瘤,此前没有报道过这种关联.
- 艾滋病毒或ART在原瘤发展中的潜在作用仍未确定.
- 艾滋病毒患者皮下结节的差异诊断应包括原瘤,以及脂瘤和脂质.
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