热应激通过血液中氧气的可用性影响奶牛的健康状况
Jia Zeng1,2, Jie Cai2, Diming Wang2
1Key Laboratory of Dairy Cow Genetic Improvement and Milk Quality Research of Zhejiang Province, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Journal of animal science and biotechnology
|September 1, 2023
概括
奶牛的热应激会损害氧的新陈代谢和运输,对牛奶生产和牛健康产生负面影响. 这项研究研究了热应激对乳牛氧气水平及其相关生物标志物的影响.
科学领域:
- 动物科学 动物科学
- 乳牛生理学 乳牛生理学
- 环境压力 环境压力
背景情况:
- 全球气温上升增加了高产奶牛的热应激风险,导致牛奶质量和产量下降.
- HS对乳制品动物氧化代谢的特定影响尚不清楚.
- 了解这些影响对于减轻乳牛健康和生产率的负面影响至关重要.
研究的目的:
- 研究氧化物代谢对乳牛健康状况的作用,乳牛经历不同程度的热应激 (没有,轻度,中度).
- 在不同的热应激条件下测量牛奶产量,牛奶成分和血液生物化学变量.
主要方法:
- 乳牛遭受了三种热应激水平:没有 (No-HS),轻度 (Mild-HS) 和中度 (Mod-HS).
- 监测了直肠温度和呼吸速率.
- 血液样本分析了氧气度,电解质 (Na+),酸平衡 (总CO2,pH),氧化应激标志物 (甲,谷氨过氧化酶),热冲击蛋白 (HSP90) 和血管生成因子 (血管内皮生长因子,血氧酶-1,缺氧诱导因子1α). 红细胞计数和血红蛋白度也被测量.
主要成果:
- 热应激显著增加了直肠温度和呼吸速率.
- 中度HS导致血液电解质平衡发生变化,关动脉和乳腺静脉的氧气度降低,HSP90,马隆迪,血管内皮生长因子,血氧酶-1和缺氧诱导因子1α增加.
- 轻度和中度HS降低了红细胞计数和尾静脉中的血红蛋白度.
结论:
- 热应激通过限制氧气代谢和运输,对奶牛的健康和哺乳产生负面影响.
- 通过HS影响乳腺功能的特定机制需要进一步研究.
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