在斯里兰卡的第三级护理机构中,对孕妇的禁食与食后甲状腺功能测试结果进行了比较研究
Shifaniya Banu Mohideen1, Thamara Herath1, Supun Manathunga2
1Department of Biochemistry, Medical Research Institute, Colombo, Sri Lanka.
Laboratory medicine
|September 2, 2023
概括
禁食和非禁食甲状腺功能测试 (TFT) 在孕妇中显示出显著的差异. 饭后的TSH水平较低,影响临床下甲状腺功能障碍症的诊断.
科学领域:
- 内分泌学 在内分泌学.
- 生殖医学 生殖医学
- 临床化学 临床化学
背景情况:
- 准确的血清甲状腺激素 (TSH) 测量对于在怀孕期间诊断亚临床甲状腺功能障碍症 (SCH) 是至关重要的.
- 甲状腺功能测试 (TFT) 是常用的,但它们相对于食物的时间往往被忽视.
研究的目的:
- 调查孕妇的禁食和非禁食状态之间的TFT显著差异.
- 评估饮食时间对怀孕期间TSH和自由T4水平的影响.
主要方法:
- 一项涉及100名怀孕母亲的研究,这些孕妇先前未被诊断出甲状腺功能障碍.
- 收集所有季度的禁食和2小时食后TFTs (TSH,自由T4).
- 禁食和食后状态之间的TSH和自由T4水平的比较.
主要成果:
- 吃饭后的TSH水平明显低 (1.01 mIU/L) 比空腹时的水平 (1.47 mIU/L) (P < .01).
- 与禁食水平 (10.70 pmol/L) 相比,食后自由T4水平也较低 (10.30 pmol/L) (P < .01).
- SCH的患病率从9.4% (禁食) 降至3.5% (食后).
结论:
- 与孕妇的禁食水平相比,食后的TSH水平显著降低.
- 饮食时间极大地影响怀孕中SCH诊断,如果不标准化,可能导致诊断不足.
- 建议对TFTs的血液采样时间进行标准化,特别是对于孕妇群体.
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