大血管封闭性中风后机械血栓切除术后中风的频率和预测因素:来自多中心队列研究的结果
Joachim Gruber1, Thomas Gattringer2,3, Georg Mayr4
1Department of Neurology 1, Neuromed Campus, Kepler University Hospital, Wagner-Jauregg-Weg 15, 4020, Linz, Austria.
Journal of neurology
|September 2, 2023
概括
脑卒中后 (PSE) 发生在9%的大血管封闭性脑卒中患者中,这些患者接受了机械血栓切除术 (MT) 治疗. 在MRI上更大的心脏病发作大小和大脑微型血流独立预测了PSE的发展.
科学领域:
- 神经学 神经学
- 脑卒中医学 脑卒中医学
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 脑卒中后 (PSE) 是中风后的一种严重并发症.
- 在接受机械血栓切除术 (MT) 的大血管封闭 (LVO) 卒中患者中,关于PSE频率和预测因子的数据有限.
- 急性和先前存在的MRI病变特征在PSE风险预测中的作用需要进一步调查.
研究的目的:
- 评估与MT治疗的急性缺血性中风患者PSE的风险.
- 确定预测PSE发展的临床和MRI特征.
- 评估在接受MT的LVO中风患者中PSE的患病率.
主要方法:
- 多中心研究包括连续急性缺血性中风患者,这些患者接受了LVO的MT.
- 分析了长期随访数据和干预后的大脑MRI.
- 通过MRI评估了心脏病的大小,受影响的区域,出血并发症和慢性脑血管疾病的特征.
主要成果:
- 研究队列包括348名患者,平均随访时间为78个月.
- 9%的患者 (32/348) 在平均477天后发展出PSE.
- 更大的心脏病发作大小和大脑微型血液的存在被确定为PSE的独立预测因素.
结论:
- 在接受MT治疗的LVO中风患者中,PSE的患病率在6.5年的中位数随访期间为9%.
- 在干预后的MRI上,心脏病发作的大小是PSE的重要预测因素.
- 大脑MRI上的脑微血流也预测了PSE在这个患者群体中的发生.
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