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胰腺切除术后的持续灌:一个系统的审查
Ilaria Pergolini1,2,3, Florian Scheufele1,2,3, Elke Demir1,2,3
1Department of Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Straße 22, 81675, Munich, Germany.
Langenbeck's archives of surgery
|September 2, 2023
概括
持续灌可能有助于预防和管理胰腺手术后的术后胰腺 (POPF). 这种技术在降低高风险患者的并发症和死亡率方面显示出有希望的结果,因此需要进一步研究.
科学领域:
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
- 胰腺手术 胰腺手术
背景情况:
- 在胰腺切除后,术后胰腺 (POPF) 仍然是一个重大挑战.
- 在选择性胰腺手术后,围胰腺区域持续灌的疗效尚未得到充分证实.
研究的目的:
- 系统地审查当前关于使用连续灌来预防或管理选择性胰腺切除后的POPF的文献.
- 评估有关这种手术技术的现有知识和专业知识.
主要方法:
- 在主要数据库 (PubMed,Scopus,Web of Science,Ovid MEDLINE) 中使用PRISMA 2020指南进行了全面的系统文献搜索.
- 由于研究异质性,进行了描述性审查,而不是统计推断.
- 系统审查在OSF注册表上预先注册.
主要成果:
- 这次审查包括了9项研究.
- 三项关于远端胰腺切除术后预防性灌的研究表明,临床相关的POPF,并发症和死亡率较低.
- 六项研究报告了使用局部洗治疗现有的POPF和液体收集的成功结果.
结论:
- 关于持续灌用于POPF预防/管理胰腺切除后的有限出版物存在.
- 有希望的结果表明,在高风险患者中具有潜在的实用性.
- 需要进一步的研究,包括随机试验,以确认疗效.
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