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丁受体基因影响小猪的行为和生长

Rafael Suárez-Mesa¹, Roger Ros-Freixedes¹, Marta Díaz²

¹Department of Animal Science, University of Lleida - Agrotecnio-CERCA Center, 25198 Lleida, Catalonia, Spain.

Journal of animal science

|September 2, 2023

概括

猪瘦素受体基因的一种特定变异显著影响从出生到断奶的小猪的活力和生长. 带有TT基因型的小猪具有更高的出生体重,更好的活力和增强的生长,部分克服了母亲的影响.

科学领域:

动物遗传学和基因组学
生殖和发育生物学生殖和发育生物学
畜牧生产和管理畜牧生产和管理

背景情况:

小猪出生时体重低与哺乳期活力下降和生长受损有关.
猪瘦素受体基因 (rs709596309) 中的一种特定的衰退变异 (C>T) 与食欲增加和肥胖有关,但其早期影响尚不清楚.
了解基因变异对幼年影响对于改善小猪的表现和生存至关重要.

研究的目的:

调查猪瘦素受体基因变异对新生猪的出生体重和活力的影响.
确定这种基因变异对母猪哺乳期生长能力和断奶时体重的影响.
评估食欲影响基因对猪早期发育阶段的影响.

主要方法:

实验涉及668只纯种Duroc猪仔和74只母猪,这些母猪的基因型为莱普受体变体 (CC,CT,TT).
猪仔在出生时被称重,并根据行为观察评估活力 (尺度1-3).
贝叶斯的2特征双变模型和责任值 (probit) 模型被用来分析基因型对出生体重,活力和断奶特征的影响.

主要成果:

与其他基因型相比,TT新生猪在出生时体重显著增加 (+28g).
在测试前,TT猪仔表现出更高的活力 (6.5%更高的高活力得分概率) 和哺乳行为.
TT猪在哺乳期 (+153g) 增长,在断奶时 (+169g) 体重更大,部分抵消了母亲的影响.

结论:

研究的瘦素受体基因变异影响小猪的出生体重,活力和从出生到断奶的生长.
TT基因型在生命早期发育方面具有优势,尽管存在潜在的负面母体影响,但它提高了小猪的表现.
调节食欲的基因,就像勒素受体基因一样,从猪的最早生命阶段就具有显著的发育影响.

关键词:

增长的增长增长的增长增长的增长.哺乳期哺乳期哺乳期叶黄素受体的受体是什么产妇对母亲的影响.猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪活力活力活力

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